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Nafila nafila
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology

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Journal : Klinikal Sains (Jurnal Analis Kesehatan)

 1 
PERBANDINGAN EFEKTIVITAS INFUSA DAN REBUSAN DAUN LANGSAT (Lansium domesticum L) DALAM MENURUNKAN KADAR GLUKOSA SECARA IN VITRO dian nurmansyah; Nafila nafila; Hayatush Shalihah; Amanah amanah
Klinikal Sains : Jurnal Analis Kesehatan Vol 10 No 1 (2022): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v10i1.2522

Abstract

Daun langsat (Lansium domesticum L) merupakan salah satu tanaman obat yang dapat mengobati penyakit diabetes. Diabetes Mellitus merupakan penyakit yang ditandai dengan kenaikan gula darah. Senyawa yang terkandung didalam daun langsat yang berfungsi dapat menurunkan kadar glukosa darah adalah flavonoid. Flavonoid bersifat protektif terhadap kerusakan sel β sebagai penghasil insulin serta dapat mengembalikan sensitifitas reseptor insulin pada sel dan bahkan meningkatkan sensitivitas insulin. Penelitian ini bertujuan untuk mengetahui perbedaan penurunan kadar glukosa secara in vitro dengan penambahan infusa dan rebusan daun langsat. Kadar glukosa diukur secara in-vitro menggunakan alat Sfektorfotometer UV-Vis dengan metode Nelson somoghy. Hasil uji skrining fitokima didapatkan senyawa flavonoid, alkaloid , tanin dan saponin positif. Hasil analisa data dengan menggunakan Independent T test didapatkan p-value 0.032 < 0.050. Dapat disimpulkan terdapat perbedaan bermakna pengukuran kadar glukosa secara in vitro dengan perlakuan pemberian infusa dan rebusan
POTENSI FILTRAT UMBI TALAS (Colocasia esculenta (L.) Schott) SEBAGAI ANTIKOAGULAN Maya Herliana Sasmitha; Shabrina Dewi Ramadhani; Muhammad Arsyad; Nafila Nafila; Dian Nurmansyah
Klinikal Sains : Jurnal Analis Kesehatan Vol 11 No 2 (2023): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v11i2.3719

Abstract

A Clinical laboratory is a health laboratory that carries out clinical specimen examination services with the type of blood test material. Blood that is used as an examination material sometimes requires additional substances that can inhibit blood clotting such as anticoagulants. Natural ingredients that are thought to have anticoagulant content are taro tuber filtrate (Colocasia esculenta (L.) Schott). This study aimed to determine the potential of taro tuber filtrate (Colocasia esculenta (L.) Schott) as an alternative anticoagulant. The method used in testing anticoagulant activity is Clotting Time in Vitro. Taro tubers are grated and filtered to obtain filtrate from taro tubers. Taro tuber filtrate test samples are divided into 5 concentrations of 10%, 30%, 50%, 70%, and 90%. Each concentration was carried out 4 times with each treatment given a blood sample of 1 mL. The results of the phytochemical screening test of taro tuber filtrate contain secondary metabolite compounds of flavonoids, alkaloids, and saponins that have anticoagulant activity. Based on the results of clotting time testing that 1 mL of blood mixed with 10% taro tuber filtrate clotted after the 15th hour, while concentrations of 30%, 50%, 70%, and 90% did not occur blood clots after observation for 6 days. Based on the results of research that has been done, it can be concluded that taro tuber filtrate (Colocasia esculenta (L.) Schott) has the potential as an alternative anticoagulant
Co-Authors Dian Nurmansyah Hayatush Shalihah Maya Herliana Sasmitha Muhammad Arsyad Shabrina Dewi Ramadhani Yoga Yuniadi